Professor Andrew Agbaje, a Nigerian researcher at the University of Eastern Finland, has received a €1.5 million European Research Council (ERC) Starting Grant to lead a five-year study into the long-term health effects of vaping among young people.
The VAPE-HABIT project will examine how vaping affects the heart, brain, kidneys, liver and metabolic health. The award is the first ERC Starting Grant secured by the Institute of Public Health and Clinical Nutrition at the University of Eastern Finland, where Agbaje is a Senior Researcher and Associate Professor of clinical epidemiology and child health.
The new project adds to a body of work examining how health behaviours and changes during childhood and adolescence can influence cardiovascular and metabolic health later in life.
A global ranking in arterial stiffness research
The grant follows Agbaje's ranking as the world's No. 1 scholar in arterial stiffness research in the November 2025 ScholarGPS global ranking.
He was also ranked first in Europe and the Nordic countries in the specialty and placed in the top 0.01 per cent of scholars worldwide in arterial stiffness research over the preceding five years, based on productivity and quality.
His research has linked childhood tobacco smoking with premature cardiac damage and found that smoking prevalence increases 15-fold between the ages of 13 and 17.
He has also identified arterial stiffness as a novel risk factor for paediatric obesity and insulin resistance, while finding adolescence to be a critical period for interrupting the pathological cycle between increasing fat mass and insulin resistance.
Other studies have shown that light-intensity physical activity can help reverse excessive fat deposition associated with childhood sedentariness.
Agbaje has also identified waist-to-height ratio as a specific surrogate for fat mass rather than muscle mass, suggesting it could replace BMI in assessing childhood obesity. The finding led to a live BBC World News interview.
VAPE-HABIT takes the research into vaping
The new ERC-funded study turns attention to youth vaping and its possible consequences across several vital systems of the body.
VAPE-HABIT will investigate the effects of vaping on young people's heart, brain, kidneys, liver and metabolic health over five years.
The subject fits within Agbaje's broader research into childhood and adolescent health, while addressing a different form of exposure from the tobacco smoking examined in his earlier work.
Recognition from the American Heart Association
Agbaje's research has been selected by the American Heart Association among major cardiovascular advances in two successive years.
In December 2024, one of his studies was named among the world's most significant advances in cardiovascular research for the year. Another was selected in December 2025 among the world's cutting-edge advances in cardiovascular medicine.
His research has also performed strongly in citation rankings. Clarivate's Web of Science placed two of his publications among the top 1 per cent of highly cited papers in Clinical Medicine in October 2023, while a third reached the top 1 per cent in Biology & Biochemistry.
He has published single- and first-authored original research in JACC, Diabetes Care and Nature Communications and is the main supervisor of seven PhD candidates.
A reach extending beyond academia
Agbaje's research generated more than 2,500 media mentions between 2022 and 2024.
The coverage appeared in international outlets including CNN, BBC, and many others.
The reports had a potential global reach of more than 4.5 billion people, with an estimated equivalent advertising value exceeding US$30 million.
His broadcast appearances included BBC Radio Devon on 16 January 2024, BBC World News on 14 March 2024 and the BBC World Service Radio Newsday programme on 15 December 2023.
The US Endocrine Society featured his research in its March 2024 Endocrine Magazine and produced a podcast interview with him. He also participated in a press conference at the ENDO 2024 congress in Boston.
The European Association for the Study of Obesity, representing professional associations from 36 European countries, has interviewed him and featured his work at the European Congress on Obesity.
Awards and international scientific work
Agbaje received the inaugural American Society of Nutrition Foundation-Novo Nordisk Foundation Flemming Quaade Award for Innovative Approaches to Childhood Obesity, worth 500,000 Danish kroner, approximately €67,000 or US$70,000.
He also received the 2024 EASO-Novo Nordisk Foundation New Investigator Award in Childhood Obesity, worth 300,000 Danish kroner, approximately €40,000 or US$44,000.
His other honours include the Paul Dudley White International Scholar Award, received five consecutive times; the Jeremiah and Rose Stamler Research Award, received twice; and the Elizabeth Barrett-Connor Research Award in Epidemiology and Prevention and Early Career Investigator Award for Preventive Cardiovascular Medicine, each received once.
He has also received an Endocrine Society Award for Outstanding Abstract, while the European Heart Journal designated him a Rising Star in Preventive Cardiology.
Agbaje leads the urFIT-child research group at the University of Eastern Finland and is principal investigator of the PAFSMEVAC project, which runs from 1 January 2020 to 31 December 2035.
His research collaborations include Nigeria, Canada, Germany, Saudi Arabia, Australia, the United Kingdom and the United States. He was an Honorary Research Fellow at the Children's Health and Exercise Research Centre at the University of Exeter from 2023 to 2026.
He is an elected Fellow of the American College of Cardiology, European Society of Cardiology, American Heart Association and New York Academy of Medicine, as well as an elected member of Sigma Xi. He is also an expert adviser to the World Health Organization and a member of the US Endocrine Society's task force on preventing childhood obesity.
A Finland-Nigeria scientific connection
The VAPE-HABIT project places a Nigerian researcher at the head of a major European study on youth vaping, while his existing research network includes collaborators in Nigeria.
Its focus also extends a line of inquiry that has run through Agbaje's work: understanding health risks early enough to identify their consequences before they become established later in life.
The €1.5 million ERC award now places youth vaping at the centre of Agbaje's next major research effort, five years after his work on childhood health began attracting international scientific and media attention. The VAPE-HABIT study will determine how far the effects of the habit extend, from the heart and brain to the kidneys, liver and metabolic system.